Tasa de catabolismo proteico normalizado (nPCR) y fragilidad en pacientes en hemodiálisis

• Sebastián ARIAS MONGE ^[1] ; Christian BURGOS TOAZA ^[1] ; Cecilia ARTEAGA-PAZMIÑO ^[1]
  1. [1] Universidad de Guayaquil

     Universidad de Guayaquil

     Guayaquil, Ecuador

     
• Localización: Nutrición clínica y dietética hospitalaria, ISSN 0211-6057, Vol. 44, Nº. 2, 2024, págs. 194-200
• Idioma: español
• DOI: 10.12873/442arteaga
• Títulos paralelos:
  • Normalized protein catabolism rate (nPCR) and frailty in hemodialysis patients
• Enlaces
  • Texto completo
• Resumen
  • español

    Introducción: La ingesta de proteínas insuficiente y la fragilidad son problemáticas frecuentes en pacientes en hemo-diálisis (HD).

    Objetivo: El objetivo de este estudio fue determinar la asociación entre la tasa de catabolismo proteico normalizado (nPCR) y la fragilidad en pacientes en HD ambulatoria. Pacientes y Métodos: Estudio transversal, realizado en el Instituto del Riñón y Diálisis “INRIDI San Martín” de Guayaquil,Ecuador. Se utilizó el nPCR como indicador indirecto de la ingesta de proteínas y se clasificó como: <1 g/kg/día (bajo), 1-1,2 g/kg/día (medio) y >1,2 g/kg/día (alto); la fragilidad se valoró con la escala FRAIL.

    Resultados: Se evaluó a 49 participantes con una edad de 58 (52,5-65,5) años, el 65,3% (n=32) eran mujeres, la media de IMC fue 27,4 ± 4,9 kg/m2 y el nPCR de 0,80 (0,67-0,93)g/kg/día. El 85,7% (n=42) presentó un nPCR bajo y 42,9%(n=22) tuvo fragilidad. No se encontró asociación entre el nPCR y la fragilidad en los sujetos estudiados (p=0,828).

    Conclusión: No existe asociación entre nPCR y fragilidad en la población estudiada

  • English

    Introduction: Low protein intake and frailty are frequent issues in hemodialysis (HD) patients.

    Aim: The aim of this study was to determine the association between the normalized protein catabolism rate (nPCR)and frailty in patients on outpatient HD.

    Methods: Cross-sectional study, conducted at the Instituto del Riñón y Diálisis “INRIDI San Martín” in Guayaquil, Ecuador.nPCR was used as a surrogate indicator of protein intake andwas classified as: <1 g/kg/day (low), 1-1.2 g/kg/day(medium), and >1.2 g/kg/day. day (high); frailty was assessed with the FRAIL scale.

    Results: 49 participants with an age of 58 (52.5-65.5)years were evaluated, 65.3% (n=32) were women, the mean BMI was 27.4 ± 4.9 kg/ m2 and the nPCR was 0.80 (0.67-0.93) g/kg/day. 85.7% (n=42) had a low nPCR and 42.9%(n=22) had frailty. No association was found between nPCRand frailty in the subjects studied (p=0.828).

    Conclusion: There is no association between nPCR and frailty in the population studied.

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