Acceso usuarios
Saad Al Fawaeir, Ali Ata Alsarhan, Ibrahim Al Odat, Alia Khwaldeh, Baker Al Shara
Background: Breast cancer is a cancerous growth impacting approximately 2.26 million women globally, The WorldHealth Organization reports that it is thought to be the tumorin women that is diagnosed the most commonly.
Objective: Examining any possible correlation between serum lipid concentrations and the cancer of the breast in acommunity sample of Jordanian women is the primary goal of the current investigation.
Methods: In this study 122 subjects were included, patient group consists of 94 women diagnosed breast cancer in oncology clinics in Jordan, where control group consists of 28 healthy women. Samples of Venous blood were collected from participant’s subjects, after centrifugation obtained serum was used for assessment of Triglycerides, total cholesterol, and HDL –cholesterol levels using fully automated analyzer for biochemistry.The Fried Wald equation was applied for calculating serum concentrations of LDL-CholesterolResults: After comparison with control group, a strong positive significant notable elevation was observed in the BMI values of the breast cancer patients. (28.8 ± 3.9 vs.25.2 ± 4.3 kg/m2, p more than 0.005). The patient group’s serumlevels of total cholesterol and triglycerides were observed tobe considerably higher than those of the control group.(230.7 ± 86.9 vs. 177.6 ± 44.5 mg/dL, p >0.005) and(209.4 ± 95.9 vs. 175.7 ± 45.6 mg/dL, p >0.005) respectively. On other hand, the patients’ group’s blood LDL-ch-lesterol levels were found to be higher (122.8 ± 25.5 vs. 115.9 ± 26.9mg/dL, p >0.005). There was no notable alteration in Serum HDL-Cholesterol levels among the two group.
Conclusion: The current study’s results indicate a clear correlation between increased body mass index (BMI), alteredlipid profiles, and an increasing of risk of breast cancer in women living in Jordan.
