Recomendaciones y consenso en el manejo terapéutico del paciente con exacerbación de EPOC en los servicios de urgencias de Castilla y León (adaptación a 2024 de directrices de GOLD 2023 y GesEPOC 2021)

Raúl Alonso Avilés; Carlos del Pozo Vegas; J.R. Casal Codesido; Vicente Priego Martínez; Joaquín Enrique Fernández de Valderrama Benavides; Jesús Jodra Peréz; Gonzalo Ibáñez Gallego; Mario Hernández Gajate; Pablo Alonso Chacón; Henar Bergaz Díez; Jorge García Criado; Daniel Muñoz Álvarez; Luis Antonio Peña Luengo; S. Escudero Alvarez; Cristina Peña Busto; Ramón Rodríguez Borrego

Recomendaciones y consenso en el manejo terapéutico del paciente con exacerbación de EPOC en los servicios de urgencias de Castilla y León (adaptación a 2024 de directrices de GOLD 2023 y GesEPOC 2021)

Alonso Avilés R ^[1] ; Del Pozo Vegas C ^[1] ; Casal Codesido JR ^[2] ; Priego Martínez V ^[3] ; Fernández de Valderrama Benavides JE ^[4] ; Jodrá Pérez JA ^[5] ; Ibáñez Gallego G ^[12] ; Hernández Gajate M ^[6] ; Alonso Chacón P ^[7] ; Bergaz Díez H ^[13] ; García Criado J ^[8] ; Muñoz Álvarez D ^[9] ; Peña Luengo LA ^[10] ; Escudero Álvarez S ^[11] ; Peña Busto C ^[14] ; Rodríguez Borrego R ^[15]
1. [1] Hospital Universitario de Valladolid
  
  Hospital Universitario de Valladolid
  
  Valladolid, España
2. [2] Hospital del Bierzo
  
  Hospital del Bierzo
  
  Ponferrada, España
3. [3] Complejo Asistencial Universitario de Burgos
  
  Complejo Asistencial Universitario de Burgos
  
  Burgos, España
4. [4] Hospital Santiago Apostol
  
  Hospital Santiago Apostol
  
  Vitoria, España
5. [5] Complejo Asistencial de Soria
  
  Complejo Asistencial de Soria
  
  Soria, España
6. [6] Hospital Universitario Pío del Río Hortega
  
  Hospital Universitario Pío del Río Hortega
  
  Valladolid, España
7. [7] Complejo Asistencial de Segovia
  
  Complejo Asistencial de Segovia
  
  Segovia, España
8. [8] Hospital Universitario de Salamanca
  
  Hospital Universitario de Salamanca
  
  Salamanca, España
9. [9] Complejo Asistencial de Ávila
  
  Complejo Asistencial de Ávila
  
  Ávila, España
10. [10] Hospital Virgen de la Concha
  
  Hospital Virgen de la Concha
  
  Zamora, España
11. [11] Complejo Asistencial Universitario de León
  
  Complejo Asistencial Universitario de León
  
  León, España
12. [12] Servicio de Urgencias, Complejo Asistencial de Palencia, España.
13. [13] Servicio de Urgencias, Hospital Comarcal de Medina del Campo, Valladolid, España.
14. [14] Servicio de Urgencias, Hospital Santos Reyes de Aranda de Duero, Burgos, España.
15. [15] Proyecto EPOC URG CyL
Mostrar afiliaciones +
Localización: Revista Española de Urgencias y Emergencias, ISSN-e 2951-6552, ISSN 2951-6544, Vol. 3, Nº. 3, 2024, págs. 172-183
Idioma: español
DOI: 10.55633/s3me/REUE016.2024
Títulos paralelos:
- Consensus and recommendations for the management of therapy in patients with exacerbated chronic obstructive pulmonary disease in the emergency services of Castile-Leon — a 2024 adaptation of the GOLD 2023 and GesEPOC 2021 guidelines
Enlaces
- Texto completo (pdf)
Referencias bibliográficas
- World Health Organization. The top 10 causes of death. (Consultado 1 Septiembre 2023). Disponible en: https://www.who.int/news-room/factsheets/detail/the-top-10-causes-of-death
- 2. Adeloye D, Chua S, Lee C, Basquill C, Papana A, Theodoratou E, et al; Global Health Epidemiology Reference Group (GHERG). Global and regional...
- Adeloye D, Song P, Zhu Y, Campbell H, Sheikh A, Rudan I. Global, regional and national prevalence of risk factors for chronic obstructive...
- Soriano JB, Alfageme I, Miravitlles M, de Lucas P, Soler-Cataluna J, García-Río F, et al. Prevalence and determinants of COPD in Spain: EPISCAN...
- Alcázar B, Trigueros JA, Riesco JA, Campuzano A, Pérez J. Geographic variations of the prevalence and distribution of COPD phenotypes in Spain:...
- Celli B, Fabbri L, Criner G, Martinez FJ, Mannino D, Vogelmeier C, et al. Definition and Nomenclature of Chronic Obstructive Pulmonary Disease:...
- Celli BR, Fabbri LM, Aaron SD, Agusti A, Brook R, Criner GJ, et al. An Updated Definition and Severity Classification of Chronic Obstructive...
- Barnes PJ. Inflammatory mechanisms in patients with chronic obstructive pulmonary disease. J Allergy Clin Immnol. 2016;138:16-27.
- Lane ND, Brewin K, Hartle TM, Gray WK, Burgess M, Steer J, et al. Specialist emergency care and COPD outcomes. BMJ Open Respiratory Research....
- Nardini S, Annesi-Maesan I, Donno MD, Delucchi M, Bettoncelli G, Lamberti V, et al. The AIMAR recommendations for early diagnosis of chronic...
- Echevarria C, Steer J, Heslop-Marshall K, Stenton SC, Hickey PM, Hughes R, et al. The PEARL score predicts 90-day readmission or death after...
- Rothnie KJ, Müllerová H, Smeeth L, Quint JK. Natural history of chronic obstructive pulmonary disease exacerbations in a general practice–based...
- Reilev M, Pottegård A, Lykkegaard J, Søndergaard J, Ingebrigtsen TS, Hallas J. Increased risk of major adverse cardiac events following the...
- Montero A. El eje cardiopulmonar y la mortalidad cardiovascular en el paciente EPOC. Medicina de Familia. SEMERGEN. 2023;49:101928.
- Iheanacho I, Zhang S, King D, Rizzo M, Ismaila A. Economic Burden of Chronic Obstructive Pulmonary Disease (COPD): A Systematic Literature...
- Agustí A, Celli BR, Criner GJ, Halpin D, Anzueto A, Barnes P, et al. Global Initiative for Chronic Obstructive Lung Disease 2023 Report: GOLD...
- Soler-Cataluña JJ, Piñera P, Trigueros JA, Calle M, Casanova C, Cosío B, et al; en representación del grupo de trabajo de GesEPOC 2021. Actualización...
- Tamondong-Lachica DR, Skolnik N, Hurst JR, Marchetti N, Rabe APJ, Montes de Oca M, et al. GOLD 2023 Update: Implications for Clinical Practice....
- Wedzicha JA, Seemungal TA. COPD exacerbations: defining their cause and prevention. Lancet. 2007;370:786-96.
- Mathers CD, Loncar D. Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med. 2006;3:e442.
- Jimenez D, Agusti A, Tabernero E, Jara-Palomares L, Hernando A, Ruiz-Artacho P, et al. Effect of a Pulmonary Embolism Diagnostic Strategy...
- Nagata K, Horie T, Chohnabayashi N, Jinta T, Tsugitomi R, Shiraki A, et al. Home High-Flow Nasal Cannula Oxygen Therapy for Stable Hypercapnic...
- Osadnik CR, Tee VS, Carson-Chahhoud KV, Picot J, Wedzicha JA, Smith BJ. Non-invasive ventilation for the management of acute hypercapnic respiratory...
- Alonso Avilés R, Casal Codesido JR, Caballero García A, del Pozo Vegas C, Gómez de Diego A, Rodríguez Borrego R, et al. Variabilidad en la...
- Alonso Avilés R, Macías García S, Elescano Barrientos KP, Heredia Moldes S, De Diego Arnaiz M, Vicario Jiménez N, et al. Diferencias en la...
- Prediletto I, Giancotti G, Nava S. COPD Exacerbation: Why It Is Important to Avoid ICU Admission. J Clin Med. 2023;12:3369.
- Austin MA, Wills KE, Blizzard L, Walters EH, Wood-Baker R. Effect of high flow oxygen on mortality in chronic obstructive pulmonary disease...
- Calverley PM, Martinez FJ, Vestbo J, Jenkins CR, Wise R, Lipson DA, et al. International differences in the frequency of chronic obstructive...
- Rabe KF, Martinez FJ, Ferguson GT, Wang C, Singh D, Wedzicha JA, et al. Triple inhaled therapy at two glucocorticoid doses in moderate-to-very-severe...
- Lipson DA, Crim C, Criner GJ, Day NC, Dransfield MT, Halpin DM, et al. Reduction in all-cause mortality with fluticasone furoate/umeclidinium/vilanterol...
- Miravitlles M, Calle M, Molina J, Almagro P, Gómez JT, Trigueros JA, et al. Actualización 2021 de la Guía Española de la EPOC (GesEPOC). Tratamiento...
- Mendoza LG, Rey JG, Carrero JT, Piñeira P. Protocolo de manejo de pacientes con enfermedad pulmonar obstructiva crónica tras agudización en...
- Spies R, Potter M, Hollamby R, van der Walt S, Hohlfeld A, Ochodo E, et al. Sputum Color as a Marker for Bacteria in Acute Exacerbations of...
- Anthonisen NR, Manfreda J, Warren CP, Hershfield ES, Harding GK, Nelson NA. Antibiotic therapy in exacerbations of chronic obstructive pulmonary...
- Torres A, Blasi F, Dartois N, Akova M. Which individuals are at increased risk of pneumococcal disease and why? Impact of COPD, asthma, smoking,...
- Couturaud F, Bertoletti L, Pastre J, Roy PM, Le Mao R, Gagnadoux F, et al. Prevalence of Pulmonary Embolism Among Patients With COPD Hospitalized...
- Stolz D, Breidthardt T, Christ-Crain M, Bingisser R, Miedinger D, Leuppi J, et al. Use of B-type natriuretic peptide in the risk stratification...
- Couturaud F, Bertoletti L, Pastre J, Roy PM, Le Mao R, Gagnadoux F, et al. Prevalence of Pulmonary Embolism Among Patients With COPD Hospitalized...
- Jimenez D, Agusti A, Tabernero E, Jara-Palomares L, Hernando A, Ruiz-Artacho P, et al. Effect of a Pulmonary Embolism Diagnostic Strategy...
- Althobiani MA, Shah AJ, Khan B, Hurst JR. Clinicians' and Researchers' Perspectives on a New Chronic Obstructive Pulmonary Disease...
- Reumkens C, Endres A, Simons SO, Savelkoul PHM, Sprooten RTM, Franssen FME. Application of the Rome severity classification of COPD exacerbations...
- Prediletto I, Giancotti G, Nava S. COPD Exacerbation: Why It Is Important to Avoid ICU Admission. J Clin Med. 2023;12:3369.
- Hurst JR, Vestbo J, Anzueto A, Locantore N, Müllerova H, Tal-Singer R, et al. Susceptibility to exacerbation in chronic obstructive pulmonary...
- Tashkin DP, Celli B, Senn S, Burkhart D, Kesten S, Menjoge S, et al. A 4-year trial of tiotropium in chronic obstructive pulmonary disease....
- Celli BR, Thomas NE, Anderson JA, Ferguson GT, Jenkins CR, Jones PW, et al. Effect of pharmacotherapy on rate of decline of lung function...
- Wedzicha JA, Seemungal TA. COPD exacerbations: defining their cause and prevention. Lancet. 2007;370:786-96.
- Seemungal TA, Donaldson GC, Paul EA, Bestall JC, Jeffries DJ, Wedzicha JA. Effect of exacerbation on quality of life in patients with chronic...
- Calverley PMA, Martinez FJ, Vestbo J, Jenkins CR, Wise R, Lipson DA, et al. International Differences in the Frequency of Chronic Obstructive...
- White AJ, Gompertz S, Stockley RA. Chronic obstructive pulmonary disease . 6: The aetiology of exacerbations of chronic obstructive pulmonary...
- Papi A, Bellettato CM, Braccioni F, Romagnoli M, Casolari P, Caramori G, et al. Infections and airway inflammation in chronic obstructive...
- Li N, Ma J, Ji K, Wang L. Association of PM2.5 and PM10 with Acute Exacerbation of Chronic Obstructive Pulmonary Disease at lag0 to lag7:...
- Liang L, Cai Y, Barratt B, Lyu B, Chan Q, Hansell AL, et al. Associations between daily air quality and hospitalisations for acute exacerbation...
- Bafadhel M, McKenna S, Terry S, Mistry V, Pancholi M, Venge P, et al. Blood eosinophils to direct corticosteroid treatment of exacerbations...
- Seemungal TA, Donaldson GC, Bhowmik A, Jeffries DJ, Wedzicha JA. Time course and recovery of exacerbations in patients with chronic obstructive...
- Donaldson GC, Law M, Kowlessar B, Singh R, Brill SE, Allinson JP, et al. Impact of Prolonged Exacerbation Recovery in Chronic Obstructive...
- Seemungal TA, Donaldson GC, Paul EA, Bestall JC, Jeffries DJ, Wedzicha JA. Effect of exacerbation on quality of life in patients with chronic...
- Hoogendoorn M, Hoogenveen RT, Rutten-van Molken MP, Vestbo J, Feenstra TL. Case fatality of COPD exacerbations: a meta-analysis and statistical...
- Martinez FJ, Han MK, Flaherty K, Curtis J. Role of infection and antimicrobial therapy in acute exacerbations of chronic obstructive pulmonary...
- National Institute for Health and Care Excellence. Chronic obstructive pulmonary disease in over 16s: diagnosis and management. 2018.
- van Geffen WH, Douma WR, Slebos DJ, Kerstjens HA. Bronchodilators delivered by nebuliser versus pMDI with spacer or DPI for exacerbations...
- Bardsley G, Pilcher J, McKinstry S, Shirtcliffe P, Berry J, Fingleton J, et al. Oxygen versus air-driven nebulisers for exacerbations of chronic...
- Barr RG, Rowe BH, Camargo CA, Jr. Methylxanthines for exacerbations of chronic obstructive pulmonary disease: metaanalysis of randomised trials....
- Alcázar-Navarrete B, Jamart L, Sánchez-Covisa J, Juárez M, Graefenhain R, Sicras-Mainar A. Clinical characteristics, treatment persistence,...
- Leuppi JD, Schuetz P, Bingisser R, Bodmer M, Briel M, Drescher T, et al. Short-term vs conventional glucocorticoid therapy in acute exacerbations...
- Alia I, de la Cal MA, Esteban A, Abella A, Ferrer R, Molina FJ, et al. Efficacy of corticosteroid therapy in patients with an acute exacerbation...
- Davies L, Angus RM, Calverley PM. Oral corticosteroids in patients admitted to hospital with exacerbations of chronic obstructive pulmonary...
- De Jong YP, Uil SM, Grotjohan HP, Postma DS, Kerstjens HA, van den Berg JW. Oral or IV prednisolone in the treatment of COPD exacerbations:...
- Maltais F, Ostinelli J, Bourbeau J, Tonnel AB, Jacquemet N, Haddon J, et al. Comparison of nebulized budesonide and oral prednisolone with...
- Stallberg B, Selroos O, Vogelmeier C, Andersson E, Ekstrom T, Larsson K. Budesonide/formoterol as effective as prednisolone plus formoterol...
- Stolz D, Hirsch HH, Schilter D, Louis R, Rakic J, Boeck L, et al. Intensif ied Therapy with Inhaled Corticosteroids and Long-Acting beta (2)-Agonists...
- Waljee AK, Rogers MA, Lin P, Singal AG, Stein JD, Marks RM, et al. Short term use of oral corticosteroids and related harms among adults in...
- Sivapalan P, Lapperre TS, Janner J, Laub RR, Moberg M, Bech CS, et al. Eosinophil-guided corticosteroid therapy in patients admitted to hospital...
- Stockley RA, O'Brien C, Pye A, Hill SL. Relationship of sputum color to nature and outpatient management of acute exacerbations of COPD....
- Masterton RG, Burley CJ. Randomized, double-blind study comparing 5 and 7-day regimens of oral levofloxacin in patients with acute exacerbation...
- Ram FS, Rodriguez-Roisin R, Granados-Navarrete A, Garcia-Aymerich J, Barnes NC. Antibiotics for exacerbations of chronic obstructive pulmonary...
- Prins HJ, Duijkers R, van der Valk P, Schoorl M, Daniels JMA, van der Werf TS, et al. CRP-guided antibiotic treatment in acute exacerbations...
- Butler CC, Gillespie D, White P, Bates J, Lowe R, Thomas-Jones E, et al. C-Reactive Protein Testing to Guide Antibiotic Prescribing for COPD...
- Chen K, Pleasants KA, Pleasants RA, Beiko T, Washburn RG, Yu Z, et al. Procalcitonin for Antibiotic Prescription in Chronic Obstructive Pulmonary...
- De la Rosa Carrillo D, López-Campos JL, Alcázar Navarrete B, Calle Rubio M, Cantón Moreno R , García-Rivero JL, et al; Comité Asesor del Documento;...
- González del Castillo J, Candel FJ, De la fuente J, Gordo F, Martín-Sánchez MJ, Menéndez R, et al. Manejo integral del paciente con reagudización...
- Couturaud F, Bertoletti L, Pastre J, Roy PM, Le Mao R, Gagnadoux F, et al. Prevalence of Pulmonary Embolism Among Patients With COPD Hospitalized...
- Jimenez D, Agusti A, Tabernero E, Jara-Palomares L, Hernando A, Ruiz-Artacho P, et al. Effect of a Pulmonary Embolism Diagnostic Strategy...
- Austin MA, Wills KE, Blizzard L, Walters EH, Wood-Baker R. Effect of high flow oxygen on mortality in chronic obstructive pulmonary disease...
- Oczkowski S, Ergan B, Bos L, Chatwin M, Ferrer M, Gregoretti C, et al. ERS clinical practice guidelines: high-flow nasal cannula in acute...
- Xia J, Gu S, Lei W, Zhang J, Wei H, Liu C, et al. High-flow nasal cannula versus conventional oxygen therapy in acute COPD exacerbation with...
- Carratalá JM, Masip J. Ventilación no invasiva en la insuficiencia cardiaca aguda: uso de CPAP en los servicios de urgencias. Emergencias....
- Gil AC, Bou BM, Ballesteros JC, Lillo JA. Asistencia ventilatoria de la insuficiencia respiratoria aguda en urgencias. Ventilación mecánica...
- Alsallakh MA, Sivakumaran S, Kennedy S, Vasileiou E, Lyons RA, Robertson C, et al. Impact of COVID-19 lockdown on the incidence and mortality...
- Ahmad FB, Anderson RN. The Leading Causes of Death in the US for 2020. JAMA. 2021;325:1829-30.
- Alsallakh MA, Sivakumaran S, Kennedy S, Vasileiou E, Lyons RA, Robertson C, et al. Impact of COVID-19 lockdown on the incidence and mortality...
- Yamaya M, Nishimura H, Deng X, Yasuda H, Deng X, Sasaki T, et al. Inhibitory effects of glycopyrronium, formoterol, and budesonide on coronavirus...
- Tashkin DP, Barjaktarevic IZ. Nebulized Treatments and the Possible Risk of Coronavirus Transmission: Where Is the Evidence? Chronic Obstr...