Examination of the Promotor Methylation of the TRIM3 Gene in Obesity

• Bugsem Hulya Oztenekecioglu ^[2] ; Eda Becer ^[3] ; Rasime Kalkan ^[1]
  1. [1] European University of Lefke

     European University of Lefke

     Turquía

     
  2. [2] Department of Medical Genetics, Faculty of Medicine, Near East University, Mersin 10,Nicosia 99138, Turkey
  3. [3] Faculty of Pharmacy, Eastern Mediterranean University, Mersin 10, Famagusta 99628, Turkey

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• Localización: Academic Journal of Health Sciences: Medicina Balear, ISSN-e 2255-0560, Vol. 39, Nº. 2, 2024, págs. 87-91
• Idioma: inglés
• DOI: 10.3306/AJHS.2024.39.02.87
• Títulos paralelos:
  • Examen de la Metilación Promotora del Gen TRIM3 en la Obesidad
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• Resumen
  • español

    Antecedentes: Es fundamental comprender las causas profundas de la obesidad, que se define como el aumento de la cantidad de grasa corporal. En la patogénesis de la obesidad influyen factores ambientales, genéticos y epigenéticos.

    Metodología: En este estudio se ha estudiado el gen TRIM3 para comprender mejor cómo se desarrolla la obesidad. El objetivo de este estudio era determinar la interacción entre la obesidad y el estado de metilación de TRIM3.

    Resultados: Sin embargo, no existían diferencias estadísticamente significativas entre los participantes obesos y el grupo de control.

    Conclusiones: Este estudio fue el primero en demostrar cómo interactúan el gen TRIM3 y la obesidad, según la bibliografía.

  • English

    Background: Understanding the root causes of obesity, which is defined as having an increased amount of body fat, is crucial.

    Pathogenesis of obesity is influenced by environmental, genetic, and epigenetic factors.

    Methods: The TRIM3 gene has been studied in this study to better understand how obesity develops. This study’s goal was to determine the interaction between obesity and the methylation status of TRIM3.

    Results: However, no statistically significant differences existed between the obese participants and the control group.

    Conclusions: This study was the first to demonstrate how the TRIM3 gene and obesity interact, according to the literature.

• Referencias bibliográficas
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