Diffuse uerine leiomyomatosis complicated with cerebral thrombosis after oral contraceptive treatment：a case report of athletic patients

• Qimin Zhou ^[1] ; Xiaohong Chen ^[1] ; Huifang Wu ^[1] ; Shouye Ma ^[1] ; Qin Wang ^[1]
  1. [1] Gansu Provincial Hospital

     Gansu Provincial Hospital

     China

     
• Localización: Revista Internacional de Medicina y Ciencias de la Actividad Física y del Deporte, ISSN-e 1577-0354, Vol. 23, Nº. 90, 2023, págs. 85-96
• Idioma: español
• Enlaces
  • Texto completo
• Resumen

  • We would like to emphasize the differentiations of diagnosis and treatment between general uterine leiomyomas and diffuse uterine leiomyomatosis (DUL), which is a kind of extremely rare disease. Levonorgestrel-releasing intrauterine system (LNG-IUS) is an attainable option provided to treat DUL with cerebral thrombosis, as a feasible novel method. Case report: A 21-year-old female patient with DUL was due to cerebral venous thrombosis caused by oral contraceptives. The patient was persistently vaginal bleeding after decreasing intracranial pressure and anticoagulant therapy for 3 days. Subsequently, a hysteroscopic submucosal myomectomy was performed to restore the normal shape of the uterine cavity, and the placement of Mirena was given after surgery, which aimly played a good role in hemostasis, prevention of severe menorrhagia and reconstruction of endometrial function. Conclusion: This case report shows that, levonorgestrel-releasing intrauterine system (LNG-IUS) is efficient and secure to treat DUL after hysteroscopic surgery, and simultaneously does not increase the risk of venous thromboembolism (VTE).

• Referencias bibliográficas
  • Braga, G. C., Brito, M. B., Ferriani, R. A., Oliveira, L. C., Garcia, A. A., Pintao, M. C., & Vieira, C. S. (2014). Oral anticoagulant...
  • Braga, G. C., Brito, M. B., Ferriani, R. A., Oliveira, L. C., Garcia, A. A., Pintao, M. C., & Vieira, C. S. (2020). Effect of...
  • Brull, E. P., Fernandes, A., Monteiro, I., Bahamondes, L., & Juliato, C. R. T. (2020). Safety and bleeding patterns of the levonorgestrel...
  • Coskun, A., Ozdemir, O., Vardar, M. A., Kiran, G., Arikan, D., & Ersoz, C. (2008). A case with diffuse uterine leiomyomatosis and review...
  • de Bastos, M., Stegeman, B. H., Rosendaal, F. R., Van Hylckama Vlieg, A., Helmerhorst, F. M., Stijnen, T., & Dekkers, O. M. (2014). Combined...
  • ERGÜDEN, D., KABASAKAL, H., & KABAKLI, F. (2020). Young-of-the-year sandbar shark, Carcharhinus plumbeus (Nardo, 1827)(Carcharhiniformes:...
  • Fedele, L., Bianchi, S., Zanconato, G., Carinelli, S., & Berlanda, N. (2004). Conservative treatment of diffuse uterine leiomyomatosis....
  • Gialeraki, A., Valsami, S., Pittaras, T., Panayiotakopoulos, G., & Politou, M. (2018). Oral Contraceptives and HRT Risk of Thrombosis....
  • Gong, Y. F., Han, W., Cui, Y., Li, L. Y., Lu, L. Y., & Ren, C. N. (2020). Therapeutic effect and underlying mechanism of Gonadotropin-releasing...
  • Karlsen, K., Hrobjartsson, A., Korsholm, M., Mogensen, O., Humaidan, P., & Ravn, P. (2018). Fertility after uterine artery embolization...
  • Khialani, D., le Cessie, S., Lijfering, W. M., Cannegieter, S. C., Rosendaal, F. R., & van Hylckama Vlieg, A. (2020). The joint effect...
  • Kido, A., Monma, C., Togashi, K., Ueda, H., Itoh, K., Fujii, S., & Konishi, J. (2003). Uterine arterial embolization for the treatment...
  • Koh, J., Kim, M. D., Jung, D. C., Lee, M., Lee, M. S., Won, J. Y., . . . Lee, K. H. (2012). Uterine artery embolization (UAE) for diffuse...
  • Li, L., Nai, M., Gao, G., & Wang, L. (2016). [Comparison among measures to prevent intrauterine adhesions after artificial abortion]....
  • Ludwig, P. E., Huff, T. J., Shanahan, M. M., & Stavas, J. M. (2020). Pregnancy success and outcomes after uterine fibroid embolization:...
  • Mulvany, N. J., Ostor, A. G., & Ross, I. (1995). Diffuse leiomyomatosis of the uterus. Histopathology, 27(2), 175-179. doi:10.1111/j.1365-2559.1995.tb00026.x
  • Nevoa, J. C., Rodrigues, R. L., Menezes, G. L., Lopes, A. R., Nascimento, H. F., Santiago, S. B., . . . Barbosa, M. S. (2017). Molecular technique...
  • Pai, D., Coletti, M. C., Elkins, M., Ladino-Torres, M., & Caoili, E. (2012). Diffuse uterine leiomyomatosis in a child. Pediatr Radiol,...
  • Pisoni, C. N., Cuadrado, M. J., Khamashta, M. A., & Hunt, B. J. (2006). Treatment of menorrhagia associated with oral anticoagulation:...
  • Roach, R. E., Helmerhorst, F. M., Lijfering, W. M., Stijnen, T., Algra, A., & Dekkers, O. M. (2015). Combined oral contraceptives:...
  • Ueda, H., Togashi, K., Konishi, I., Kataoka, M. L., Koyama, T., Fujiwara, T., . . . Konishi, J. (1999). Unusual appearances of uterine leiomyomas:...
  • Zhang, X., Tian, T., Zhu, J., Lin, B., Feng, X., Zhang, L., . . . Aili, A. (2020). High intensity focused ultrasound treatment for diffuse...
  • Zhao, H., Yang, B., Li, H., Xu, Y., & Feng, L. (2019). Successful Pregnancies in Women with Diffuse Uterine Leiomyomatosis after...