Evaluation of the effect of silver nanoparticles in root canal treatment: A systematic review and meta-analysis

• Elnaz Mousavi ^[1] ; Navid Kerayechian ^[2] ; Maryam Khalili ^[3] ; Ceren Yeniay ^[4] ; Mahsa Fatahi ^[5] ; Samira Jamali ^[6]
  1. [1] Dental Sciences Research Center, Department of Endodontics, School of Dentistry, Guilan University of Medical Sciences, Rasht, Iran
  2. [2] Biomaterials Division, Department of Molecular Pathobiology, College of Dentistry, New York University, New York, United States
  3. [3] Department of Endodontics, School of Dentistry, Hamadan University of Medical Sciences, Hamadan, Iran
  4. [4] Department of Endodontics, School of Dentistry, Ataturk University, Erzurum, Turkey
  5. [5] Department of Operative Dentistry, Faculty of Dentistry, Kerman University of Medical Sciences, Kerman, Iran
  6. [6] Department of Endodontics, Stomatological Hospital, College of Stomatology, Xi’an Jiaotong University, Shaanxi, PR China

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• Localización: Academic Journal of Health Sciences: Medicina Balear, ISSN-e 2255-0560, Vol. 38, Nº. 1, 2023, págs. 85-91
• Idioma: inglés
• DOI: 10.3306/AJHS.2023.38.01.85
• Títulos paralelos:
  • Evaluación del efecto de las nanopartículas de plata en el tratamiento del conducto radicular: revisión sistemática y metanálisis
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• Resumen
  • español

    Objetivos: El presente estudio se realizó para evaluar el efecto de las nanopartículas de plata en el tratamiento de conductos radiculares.Métodos: Se incluyen todos los artículos publicados en bases de datos internacionales como PubMed, Scopus, Science Direct, ISI Web of Knowledge y Embase hasta julio de 2022. Se calculó un intervalo de confianza (IC) del 95% para el tamaño del efecto con un modal de efectos fijos. El análisis de datos se realizó utilizando el software Stata/MP.V17.Resultados: En la revisión inicial se revisaron los resúmenes de 141 estudios, dos autores revisaron el texto completo de 30 estudios y finalmente se seleccionaron ocho estudios. La eficacia de las nanopartículas de plata en comparación con el grupo control fue del 86 % (ES: 95 % IC, 0,39 a 1,33; p<0,001).Conclusiones: Según los hallazgos del presente metanálisis, las AgNP tienen un alto efecto antimicrobiano en la prevención de la persistencia de microorganismos en el conducto radicular.

  • English

    Objective: The present study was conducted to evaluate the effect of silver nanoparticles in root canal treatment.Methods: All articles published in international databases such as PubMed, Scopus, Science Direct, ISI Web of knowledge, and Embase until July 2022 included. A 95% confidence interval (CI) for effect size with a fixed effect modal was calculated. Data analysis was performed using Stata/MP.V17 software.Results: In the initial review, the abstracts of 141 studies were reviewed, two authors reviewed the full text of 30 studies, and finally, eight studies were selected. The effectiveness of silver nanoparticles compared to the control group was 86% (ES: 95% CI, 0.39 to 1.33; p<0.001). Conclusions: Based on the findings of the present meta-analysis, AgNPs have a high antimicrobial effect in preventing the persistence of microorganisms in the root canal.

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