Thamires Ribeiro Chaves, Raquel Patrícia Ataíde Lima, Marina Ramalho Ribeiro, Vitor Ferreira Boico, Flávia Emília Leite de Lima Ferreira, Maria da Conceição Rodrigues Gonçalves, Aléssio Tony Cavalcanti de Almeida, Ronei Marcos De Moraes, Alexandre Sérgio Silva, Glêbia Alexa Cardoso, Roberto Teixeira de Lima, Maria José de Carvalho Costa, Rafaella Cristhine Pordeus Luna
Background: Research regarding the correlation betweenobesity and oxidative stress is important due to the healthcomplications they entail and elucidating this associationthrough the waist-to-height ratio is of great interest becauseit is an important anthropometric indicator of cardiovascularand metabolic diseases’ risk associated with obesity. The aimof this study was to gain a better understanding of the asso-ciation between waist-to-height ratio and total antioxidant ca-pacity and malondialdehyde values in adults. Methods: A cross-sectional population-based study wasconducted in 265 individuals from a municipality in north-eastern Brazil. Epidemiological data were collected, and an-thropometric and biochemical evaluations were performed. Toachieve the objectives proposed by the study, linear regres-sion was performed. Results: In the total sample, more than half of the partic-ipants were overweight or obese. The mean value of 54 cm(SD±10) waist-to-height ratio, with the majority of adults(65.28%) presenting with slight elevation waist-to-height ra-tio. A correlation was found between waist-to-height ratio andBMI with the values of total antioxidant capacity (t= -2.96;p=0.003) and malondialdehyde (t=2.87, p=0.004), as well asLDL (t=3.19, p=0.002), triglycerides (t=3.17; p=0.002). Conclusion: Abdominal obesity, reflected by a slight ele-vation in the waist-to-height ratio, corroborated by BMI wasindicated as an aggravating factor in oxidative stress increasebecause it was positively related with malondialdehyde valuesand negatively with total antioxidant capacity values in thisadult population