Acceso usuarios
Lorena Belén, Laura Maffei, María Beatriz Alorda, Celeste Squillace, María Laura Rossi, María Laura Oliva, María Elena Torresani
Introducción: El hipotiroidismo se asocia con factores de riesgo cardiometabólicos (FRC) además de la edad y del sexo femenino. El principal objetivo fue conocer la prevalencia de hipotiroidismo y su asociación con FRC en mujeres adultas concurrentes a un Centro de Endocrinología de la Ciudad Autónoma de Buenos Aires, Argentina.
Material y Métodos: Diseño transversal y observacional en muestra no probabilística de 316 mujeres adultas (40 a 65 años), categorizadas en hipotiroideas controladas con tratamiento farmacológico y eutiroideas. Variables: Se estudiaron los siguientes FRC: Índice Masa Corporal (IMC), <25kg/m2 y ≥25,0Kg/m2; circunferencia cintura (CC) ≤88cm y >88cm; etapa biológica (premenopausia y posmenopausia), tabaquismo, sedentarismo; perfil lipídico alterado (ColT>200mg/dl; LDL-c>130mg/dl; Tg>150mg/dl; HDL-c<40mg/dl); HTA≥120/80mmHg y glucemia basal aumentada >100mg/dl. Estadística con SPSS 15.0 estableciendo medidas de tendencia central, ANOVA y OR con intervalos de confianza 95% (IC) y diferencia de proporciones con valor p<0,05.
Resultados: 46,2% hipotiroideas controladas y 53,8% eutiroideas; 64,2% posmenopáusicas; 68% con sobrepeso u obesidad y 45,2% con CC aumentada. La edad fue similar en ambos grupos: 53,3 (DS=6,4) años hipotiroideas y 53,9 (DS=6,6) años eutiroideas. Sedentarismo fue el FRC más prevalente en ambos grupos. Las hipotiroideas presentaron más riesgo de IMC aumentado (OR=0,36 IC95%=0,21-0,59; p=0,0001) y CC alterada (OR=0,53 IC95%=0,34-0,84; p=0,006) que las eutiroideas.
Conclusiones: La prevalencia de hipotiroidismo se presentó aproximadamente en la mitad de la muestra. El estado nutricional alterado fue el único FRC asociado significativamente con el hipotiroidismo.
Introduction: It is known that hypothyroidism is associated with cardiometabolic risk factors (CRF) as well as age, female gender. The main objective was determine the prevalence of hypothyroidism and its association with cardiometabolic risk factors in adult women attending the Foundation for Endocrine Metabolic Diseases Research of the Autonomous City of Buenos Aires, Argentina.
Material and Methods: Cross-sectional and observational design. Probabilistic sample of 316 adult women (40-65 years), randomized into two groups: hypothyroid controlled with pharmacological treatment and euthyroid. Variable: the following were studied CRF: body mass index (BMI), normal <25kg/m2 and increased ≥25.0kg/m2; waist circumference (WC) normal ≤88cm and increased >88cm; biological stage (premenopausal and postmenopausal), smoking, sedentary lifestyle; altered lipid profile (TC>200mg/dl; LDL>130mg/dl; Tg>150mg/dl; HDL-c<40mg/dl); HT≥120/80mmHg and increased fasting glucose >100mg/dl. Statistics with SPSS 15.0 establishing measures of central tendency, ANOVA and OR with 95% confidence intervals (CI) and difference of proportions with p<0.05.
Results: The 46.2% of the sample were women controlled hypothyroid and euthyroid 53.8%. The 64.2% were postmenopausal, 68% overweight or obese and 45.2% with WC increased. Age was similar in both groups: 53.3 (SD=6.4) years the hypothyroid and 53.9 (SD=6.6) years the euthyroid. The inactivity was the CFR more prevalent in both groups. The hypothyroid women had a significantly higher risk for BMI increased (OR=0.36; 95%CI=0.21-0.59; p=0.0001) and WC altered (OR=0.53; 95%CI=0.34-0.84; p=0.006) with respect to the euthyroid women.
Conclusions: Found a prevalence of hypothyroidism in approximately half of the sample. The altered nutritional status CRF was the only significantly associated with hypothyroidism.
