Many reports in literature have underlined particular features of Lactobacillus paracasei subsp paracasei F19, however a critical review of main clinical outcomes has not been performed so far. A summary of the most relevant reports, in terms of clinical benefiMany reports in literature have underlined particular features of Lactobacillus paracasei subsp paracasei F19, however a critical review of main clinical outcomes has not been performed so far. A summary of the most relevant reports, in terms of clinical benefits, on the usefulness of this lactic acid bacteria is given; moreover an overview of its history and an introduction of new interesting perspectives for its use in clinical practice are described.ts, on the usefulness of this lactic acid bacteria is given; moreover an overview of its history and an introduction of new interesting perspectives for its use in clinical practice are described.