A comprehensive review of the literature of the universal experience of living on the edge is discussed. Literature was reviewed from biology, criminology, ecology, economics, ethics, finance, fine arts, historical biography, medicine, nursing, philosophy, physiology, psychology, sociology, and theology. Three themes emerged with this literature review: living on the edge as a sacred place one travels to or where one lives, living on the edge as a choice in taking risks and surviving danger, and living on the edge as engaging with health experiences in which persons and nurses coparticipate. Living on the edge is a visionary quest into a new frontier that holds illimitable possibilities that transform the world. The literature is discussed according to theoretical and research findings.