The impact of low-dose enteral nutrition administered at varying rates on gastric emptying in patients with large hemispheric infarction undergoing therapeutic hypothermia: a retrospective analysis

• Miao Li ^[1] ; Wenya Cao ^[1] ; Linlin Fan ^[1] ; Fei Tian ^[1]
  1. [1] Neurocritical Care Unit. Department of Neurology. Xuanwu Hospital. Capital Medical University. National Clinical Research Center for Geriatric Disease. Beijing, People’s Republic of China
• Localización: Nutrición hospitalaria: Órgano oficial de la Sociedad Española de Nutrición Clínica y Metabolismo (SENPE), ISSN-e 1699-5198, ISSN 0212-1611, Vol. 43, Nº. 1, 2026, págs. 3-8
• Idioma: inglés
• DOI: 10.20960/nh.05849
• Títulos paralelos:
  • El impacto de la nutrición enteral en dosis bajas, administrada a tasas variables, sobre el vaciado gástrico en pacientes con infarto hemisférico grande sometidos a hipotermia terapéutica: un análisis retrospectivo
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• Resumen
  • español

    Objetivo: comprender el vaciamiento gástrico a diferentes tasas de nutrición enteral en dosis bajas es crucial para la gestión de la alimentación enteral durante la hipotermia terapéutica (HT).

    Métodos: este estudio revisó retrospectivamente los registros de 42 pacientes que recibieron HT en una única unidad de cuidados intensivos neurológicos. Los pacientes recibieron alimentación a razón de 10 ml/h o 30 ml/h. Los volúmenes residuales gástricos (VRG) se recolectaron diariamente durante 7 días durante la HT. Además, también se recolectaron las características demográficas y la gravedad de la enfermedad (puntuación APACHE-II).

    Resultados: los VRG en el grupo de 30 ml/h fueron significativamente más altos que en el grupo de 10 ml/h (p < 0,05). Ambos grupos mostraron un aumento inicial de los VRG, alcanzando el pico el día 2 (39,99 ± 17,73 ml vs. 102,74 ± 43,19 ml, p = 0,000), seguido de una disminución gradual. No hubo diferencia significativa en cuanto a vómitos (4,0 % vs. 11,8 %, p = 0,079) o a la incidencia de la neumonía asociada a ventilador (NAV) (8,0 % vs. 17,6 %, p = 0,898) entre los grupos.

    Conclusiones: los pacientes con infarto hemisférico grande probablemente toleren una tasa inicial de alimentación de 30 ml/h durante la HT.

    Las tasas de alimentación deben aumentarse gradualmente a partir del día 3 en función de la condición del paciente

  • English

    Purpose: understanding gastric emptying at different rates of low-dose enteral nutrition is crucial for managing enteral feeding during therapeutic hypothermia (TH).

    Methods: this study retrospectively reviewed the records of 42 patients who received TH at a single neurological intensive care unit. Patients received either 10 ml/h or 30 ml/h feeding. The gastric residual volumes (GRVs) were collected daily for 7 days during TH. In addition, demographic characteristics and disease severity (APACHE-II score) were also collected.

    Results: GRVs in the 30 ml/h group were significantly higher than in the 10 ml/h group (p < 0.05). Both groups showed an initial increase in GRVs, peaking on day 2 (39.99 ± 17.73 ml vs 102.74 ± 43.19 ml, p = 0.000), followed by a gradual decrease. There was no significant difference in vomiting (4.0 % vs 11.8 %, p = 0.079) or ventilator associated pneumonia (VAP) incidence (8.0 % vs 17.6 %, p = 0.898) between the groups.

    Conclusions: patients with large hemispheric infarction may likely tolerate an initial feeding rate of 30 ml/h during TH. Feeding rates should be gradually increased from day 3 based on patient condition

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