Síndrome de Stevens-Johnson por alopurinol en una mujer portadora del alelo HLA-B*58:01

• Marina de la Puente Alonso ^[1] ; Jorge Martín-Nieto González ^[1] ; Luis Ángel Zamarro Díaz ^[1] ; Paloma García Piqueras ^[1]
  1. [1] Servicio de Dermatología, Hospital General Universitario Gregorio Marañón, Madrid, España. Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Madrid, España.
• Localización: Piel: Formación continua en dermatología, ISSN 0213-9251, Vol. 40, Nº. 8 (Octubre), 2025, págs. 549-551
• Idioma: español
• DOI: 10.1016/j.piel.2024.11.019
• Títulos paralelos:
  • Stevens-Johnson syndrome due to allopurinol in a carrier of the HLA-B*58:01 allele
• Texto completo no disponible (Saber más ...)
• Referencias bibliográficas
  • Frantz R, Huang S, Are A, et al. Stevens-Johnson syndrome and toxic epidermal necrolysis: a review of diagnosis and management. Med Kaunas...
  • Roujeau JC, Kelly JP, Naldi L, et al. Medication use and the risk of Stevens–Johnson syndrome or toxic epidermal necrolysis. N Engl J Med....
  • Kohanim S, Palioura S, Saeed HN, et al. Stevens-Johnson syndrome/toxic epidermal necrolysis – a comprehensive review and guide to therapy....
  • Somkrua R, Eickman EE, Saokaew S, et al. Association of HLAB*5801 allele and allopurinol-induced Stevens Johnson syndrome and toxic epidermal...
  • Chung WH, Hung SI, Yang JY, et al. Granulysin is a key mediator for disseminated keratinocyte death in StevensJohnson syndrome and toxic epidermal...
  • Harr T, French LE. Toxic epidermal necrolysis and StevensJohnson syndrome. Orphanet J Rare Dis. 2010;5:39. https://doi. org/10.1186/1750-1172-5-39.
  • Zimmermann S, Sekula P, Venhoff M, et al. Systemic immunomodulating therapies for Stevens-Johnson syndrome and toxic epidermal necrolysis:...
  • Lavu A, Thiriveedi S, Thomas L, et al. Clinical utility of HLAB*58:01 genotyping to prevent allopurinol-induced SJS/TEN. Hosp Pharm. 2021;56(6):660–663....
  • Sukasem C, Jantararoungtong T, Koomdee N. Pharmacogenomics research and its clinical implementation in Thailand: lessons learned from the...
  • Profaizer T, Eckels D. HLA alleles and drug hypersensitivity reactions. Int J Immunogenet. 2012;39(2):99–105. https://doi.org/ 10.1111/j.1744-313X.2011.01061.x.