Valor diagnóstico del contraste hepatoespecífico en resonancia magnética para la detección de hepatocarcinoma en pacientes con cirrosis: comparación con tomografía computarizada

• Autores: Karen Mishell Santamaria Salazar, José Patricio Beltrán Carreño
• Localización: Revista Sanitaria de Investigación, ISSN-e 2660-7085, Vol. 6, Nº. 5, 2025
• Idioma: español
• DOI: 10.34896/RSI.2025.66.60.001
• Enlaces
  • Texto completo
• Resumen
  • español

    El hepatocarcinoma (HCC) constituye la neoplasia primaria hepática más frecuente, siendo responsable de una importante carga de morbimortalidad a nivel global. De acuerdo con datos recientes del GLOBOCAN 2020, representa la tercera causa de muerte por cáncer en el mundo1.

    Este estudio corresponde a una revisión bibliográfica sistematizada con enfoque narrativo-comparativo, cuyo objetivo principal fue analizar el rendimiento diagnóstico de la resonancia magnética (RM) con contraste hepatoespecífico (ácido gadoxético disódico, Gd-EOB-DTPA) frente a la tomografía computarizada (TC) trifásica, en la detección de hepatocarcinoma (HCC) en pacientes con cirrosis hepática.

    En conclusión, la RM con contraste hepatoespecífico se posiciona como una herramienta de alta eficacia para el diagnóstico temprano de HCC en pacientes con cirrosis hepática. Su incorporación en programas de vigilancia puede mejorar significativamente los desenlaces clínicos mediante la identificación precoz de lesiones candidatas a tratamiento curativo.

  • English

    hepatocellular carcinoma (HCC) is the most common primary liver neoplasm, responsible for a significant burden of morbidity and mortality worldwide. According to recent data from GLOBOCAN 2020, it is the third leading cause of cancer-related death worldwide.

    This study is a systematic literature review with a narrative-comparative approach. The main objective of this study was to analyze the diagnostic performance of magnetic resonance imaging (MRI) with liver-specific contrast (gadoxetic acid disodium, Gd-EOB-DTPA) versus triphasic computed tomography (CT) in the detection of hepatocellular carcinoma (HCC) in patients with liver cirrhosis.

    In conclusion, MRI with liver-specific contrast is positioned as a highly effective tool for the early diagnosis of HCC in patients with liver cirrhosis. Its incorporation into surveillance programs can significantly improve clinical outcomes by early identification of lesions suitable for curative treatment.

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