Control del exudado en heridas crónicas: enfoques actuales y perspectivas futuras

• Autores: Jose Carlos Espín Giménez, Francisco José Ortega Teruel, Javier José Bermúdez Cervilla, Paola Borraz Luño, Yolanda Naya Mateu, Inés Galve Franco
• Localización: Revista Sanitaria de Investigación, ISSN-e 2660-7085, Vol. 6, Nº. 4, 2025
• Idioma: español
• Enlaces
  • Texto completo
• Resumen
  • español

    El manejo adecuado del exudado en heridas crónicas es un aspecto crítico para promover la cicatrización y prevenir complicaciones. Este artículo revisa los enfoques actuales para el control del exudado, incluyendo el uso de apósitos avanzados, terapias tópicas y estrategias basadas en evidencia. Además, se discuten las perspectivas futuras, como el desarrollo de biomateriales inteligentes y terapias personalizadas. La evidencia sugiere que un enfoque multimodal, adaptado a las necesidades individuales del paciente, es esencial para optimizar los resultados clínicos. Este trabajo también aborda los desafíos actuales en la gestión del exudado, como la variabilidad en la práctica clínica y las limitaciones económicas en entornos de bajos recursos.

  • English

    Proper management of exudate in chronic wounds is a critical aspect of promoting healing and preventing complications. This article reviews current approaches to exudate control, including the use of advanced dressings, topical therapies, and evidence-based strategies. Additionally, future perspectives, such as the development of smart biomaterials and personalized therapies, are discussed. Evidence suggests that a multimodal approach, tailored to the individual needs of the patient, is essential to optimize clinical outcomes. This work also addresses current challenges in exudate management, such as variability in clinical practice and economic limitations in low-resource settings.

• Referencias bibliográficas
  • Jones V, Grey JE, Harding KG. Wound exudate: composition and functions. Br J Community Nurs. 2006;11(9):S4-S9.
  • World Union of Wound Healing Societies (WUWHS). Principles of best practice: Wound exudate and the role of dressings. Wounds International....
  • Cutting KF. Wound exudate: composition and functions. Br J Nurs. 2003;12(11 Suppl):S4-S9.
  • Schultz GS, Sibbald RG, Falanga V, et al. Wound bed preparation: a systematic approach to wound management. Wound Repair Regen. 2003;11 Suppl...
  • Falanga V. Growth factors and chronic wounds: the need to understand the microenvironment. J Dermatol. 1992;19(11):667-672.
  • Trengove NJ, Stacey MC, MacAuley S, et al. Analysis of the acute and chronic wound environments: the role of proteases and their inhibitors....
  • O’Meara S, Al-Kurdi D, Ologun Y, Ovington LG. Antibiotics and antiseptics for venous leg ulcers. Cochrane Database Syst Rev. 2014;(1):CD003557...
  • Boateng JS, Matthews KH, Stevens HN, Eccleston GM. Wound healing dressings and drug delivery systems: a review. J Pharm Sci. 2008;97(8):2892-2923.
  • Lansdown AB. Silver in health care: antimicrobial effects and safety in use. Curr Probl Dermatol. 2006;33:17-34.
  • Queen D, Orsted H, Sanada H, Sussman G. A dressing history. Int Wound J. 2004;1(1):59-77.
  • Thomas S. Alginate dressings in wound management. Nurs Times. 1992;88(34):63-66.
  • Harding KG, Jones V, Price P. Topical treatment: which dressing to choose. Diabetes Metab Res Rev. 2000;16 Suppl 1:S47-S50 .
  • White RJ, Cooper R, Kingsley A. Wound colonization and infection: the role of topical antimicrobials. Br J Nurs. 2001;10(9):563-578.
  • Steed DL. Clinical evaluation of recombinant human platelet-derived growth factor for the treatment of lower extremity diabetic ulcers. J...
  • Barrientos S, Stojadinovic O, Golinko MS, et al. Growth factors and cytokines in wound healing. Wound Repair Regen. 2008;16(5):585-601.
  • Kamoun EA, Kenawy ES, Chen X. A review on polymeric hydrogel membranes for wound dressing applications: PVA-based hydrogel dressings. J Adv...
  • Gottrup F, Apelqvist J, Price P. Outcomes in controlled and comparative studies on non-healing wounds: recommendations to improve the quality...
  • Snyder RJ, Hanft JR. Diabetic foot ulcers—effects on quality of life, costs, and mortality and the role of standard wound care and advanced-care...
  • Boulton AJ, Vileikyte L, Ragnarson-Tennvall G, Apelqvist J. The global burden of diabetic foot disease. Lancet. 2005;366(9498):1719-1724.
  • Gupta B, Agarwal R, Alam MS. Textile-based smart wound dressings. Indian J Fibre Text Res. 2010;35:174-187.
  • Kamoun EA, Kenawy ES, Chen X. A review on polymeric hydrogel membranes for wound dressing applications: PVA-based hydrogel dressings. J Adv...
  • Singer AJ, Clark RA. Cutaneous wound healing. N Engl J Med. 1999;341(10):738-746.
  • Argenta LC, Morykwas MJ. Vacuum-assisted closure: a new method for wound control and treatment: clinical experience. Ann Plast Surg. 1997;38(6):563-576.
  • Murphy SV, Atala A. 3D bioprinting of tissues and organs. Nat Biotechnol. 2014;32(8):773-785.
  • Gottrup F. A specialized wound-healing center concept: importance of a multidisciplinary department structure and surgical treatment facilities...
  • Sen CK, Gordillo GM, Roy S, et al. Human skin wounds: a major and snowballing threat to public health and the economy. Wound Repair Regen....