Tumor fibroso solitario del sistema nervioso central: desentrañando su diagnóstico, tratamiento y seguimiento

• Autores: Ana Aliaga Chueca, Claudia Laborda Díaz, Ana Galán García, Gemma Liria Fernández, Claudia Colom Plá, Arancha Ayete Andreu
• Localización: Revista Sanitaria de Investigación, ISSN-e 2660-7085, Vol. 6, Nº. 3, 2025
• Idioma: español
• Enlaces
  • Texto completo
• Resumen
  • español

    El tumor fibroso solitario (TFS) cerebral es una neoplasia infrecuente del sistema nervioso central con características clínicas, diagnósticas y pronósticas variables. Este artículo revisa sus principales aspectos, incluyendo la presentación clínica, el diagnóstico mediante imágenes y técnicas histopatológicas, así como el manejo terapéutico basado en la resección quirúrgica y la radioterapia adyuvante en casos seleccionados. También se discuten las implicaciones pronósticas y las estrategias de seguimiento, debido al riesgo de recurrencia y metástasis a largo plazo. La evaluación multidisciplinaria y el seguimiento prolongado son esenciales para mejorar los resultados en estos pacientes.

  • English

    Cerebral solitary fibrous tumor is a rare neoplasm of the central nervous system with variable clinical, diagnostic, and prognostic features. This article reviews its main aspects, including clinical presentation, diagnosis through imaging and histopathological techniques, as well as therapeutic management based on surgical resection and adjuvant radiotherapy in selected cases. Prognostic implications and follow-up strategies are also discussed due to the risk of long-term recurrence and metastasis. Multidisciplinary evaluation and prolonged follow-up are essential to improving outcomes in these patients.

• Referencias bibliográficas
  • Louis DN, Perry A, Wesseling P, et al. The 2021 WHO Classification of Tumors of the Central Nervous System: a summary. Neuro Oncol. 2021;23(8):1231-1251.
  • Goodwin CR, Keating RF, Hwang L, et al. Solitary fibrous tumor of the central nervous system: Clinical features and outcome. J Neurosurg....
  • Schiariti M, Goetz P, El-Maghraby H, et al. Solitary fibrous tumor/hemangiopericytoma of the CNS: a review of clinical, pathological, and...
  • Zhang J, Hu B, Chen H, et al. MRI features and diagnostic strategies of intracranial solitary fibrous tumors: A retrospective study of 18...
  • Demicco EG, Park MS, Araujo DM, et al. Solitary fibrous tumor: a clinicopathological study of 110 cases and proposed risk assessment model....
  • Yang SY, Park CK, Kim SK, et al. Solitary fibrous tumors in the central nervous system: Clinicopathologic and radiologic spectrum. Acta Neurochir....
  • Ghia AJ, Chang EL, Allen PK, et al. Outcomes after proton therapy for aggressive meningiomas: A retrospective study. Radiother Oncol. 2013;107(3):366-372.
  • Rutkowski MJ, Sughrue ME, Kane AJ, et al. Predictors of mortality following treatment of intracranial hemangiopericytoma. J Neurosurg. 2010;113(2):301-307.
  • Faramand A, Rahman M, Golby A, et al. Solitary fibrous tumor/hemangiopericytoma: clinical characteristics and outcomes of intracranial and...
  • Stacchiotti S, Sommer J. Rare cancer treatment: What do we do now and where do we go? Eur J Cancer. 2015;51(3):247-250.
  • Spaltenstein M, Vajtai I, Reinert M, et al. Long-term follow-up of intracranial solitary fibrous tumor/hemangiopericytoma: A single-institution...
  • Liu XY, Wang Y, Chen FF, et al. Long-term follow-up strategies for intracranial solitary fibrous tumors: Review of 20 cases. Neurosurgery....
  • Spaltenstein M, Vajtai I, Reinert M, et al. Long-term follow-up of intracranial solitary fibrous tumor/hemangiopericytoma: A single-institution...
  • Ghia AJ, Chang EL, Allen PK, et al. Outcomes after stereotactic radiotherapy for intracranial solitary fibrous tumor/hemangiopericytoma. Radiother...
  • Rutkowski MJ, Sughrue ME, Kane AJ, et al. The role of radiotherapy in the treatment of intracranial solitary fibrous tumors. Neurosurg Rev....
  • Mizumoto M, Oshiro Y, Yamamoto T, et al. Proton beam therapy for aggressive meningiomas and solitary fibrous tumors: A retrospective study....