Exploring the mechanisms of bacterial resistance: implications for treatment strategies and public health

• Autores: Celene Lisseth Larcos Herrera, Jennifer Estefanía López Naveda, Sharon Maite García Acosta, Jessica Paola Montero Moposita, Josselyn Araceli Chicaiza Changoluisa, Carlota Alexandra Rivera Jarrin, Jennifer Geovanna Salazar Gongora
• Localización: Revista Sanitaria de Investigación, ISSN-e 2660-7085, Vol. 6, Nº. 3, 2025
• Idioma: inglés
• DOI: 10.34896/RSI.2025.45.22.001
• Enlaces
  • Texto completo
• Resumen
  • español

    Este artículo busca profundizar en los complejos mecanismos de la resistencia bacteriana, evaluar sus implicaciones para las estrategias de tratamiento y describir los desafíos y soluciones de salud pública necesarios para combatir este problema acuciante.

  • English

    This paper aims to delve into the intricate mechanisms of bacterial resistance, evaluate the implications for treatment strategies, and outline the public health challenges and solutions necessary to combat this pressing issue.

• Referencias bibliográficas
  • Fletcher S. Understanding the contribution of environmental factors in the spread of antimicrobial resistance. Environmental Health and Preventive...
  • Tao S, Chen H, Li N, Wang T, Liang W. The Spread of Antibiotic Resistance Genes in Vivo Model. The Canadian Journal of Infectious Diseases...
  • Sultan I, Rahman S, Jan AT, Siddiqui MT, Mondal AH, Haq QMR. Antibiotics, Resistome and Resistance Mechanisms: A Bacterial Perspective. Frontiers...
  • Department of Health and Human Services. How Antibiotic Resistance Moves Directly Germ to Germ [Internet]. 2023 [cited 2025 Feb 7]. Available...
  • Gaurav A, Bakht P, Saini M, Pandey S, Pathania R. Role of bacterial efflux pumps in antibiotic resistance, virulence, and strategies to discover...
  • Yu EW, Zhang Q, Brown MH. Microbial Efflux Pumps: Current Research [Internet]. Caister.com. 2024 [cited 2025 Feb 6]. Available from: https://doi.org/10.21775/9781910190753
  • Nishino K, Yamasaki S, Nakashima R, Zwama M, Hayashi-Nishino M. Function and Inhibitory Mechanisms of Multidrug Efflux Pumps. Frontiers in...
  • Lorusso AB, Carrara JA, Barroso CDN, Tuon FF, Faoro H. Role of Efflux Pumps on Antimicrobial Resistance in Pseudomonas aeruginosa. International...
  • Chiang AD, Dekker JP. Efflux pump-mediated resistance to new beta lactam antibiotics in multidrug-resistant gram-negative bacteria. Communications...
  • World Health Organization. ANTIMICROBIAL RESISTANCE Global Report on Surveillance [Internet]. 2014 [cited 2025 Feb 6]. Available from: https://apps.who.int/iris/bitstream/handle/10665/112642/9789241564748_eng.pdf
  • Batchelder JI, Hare PJ, Mok WWK. Resistance-resistant antibacterial treatment strategies. Frontiers in Antibiotics [Internet]. 2023 [cited...
  • Murray CJL. Global burden of bacterial antimicrobial resistance 1990–2021: a systematic analysis with forecasts to 2050 [Internet]. Doi.org....
  • Markley JD, Bernard S, Delacruz O. Combination Antibiotic Therapy for the Definitive Management of Select Multidrug-Resistant Gram-Negative...
  • Tufts University. What Is Combination Drug Therapy? [Internet]. Tufts.edu. 2022 [cited 2025 Feb 6]. Available from: https://medicine.tufts.edu/news-events/news/what-combination-drug-therapy
  • Urban-Chmiel R, Marek A, Stępień-Pyśniak D, Wieczorek K, Dec M, Nowaczek A, et al. Antibiotic Resistance in Bacteria—A Review. Antibiotics...
  • Hutchings MI, Truman AW, Wilkinson B. Antibiotics: past, Present and Future. Current Opinion in Microbiology [Internet]. 2019 Oct [cited 2025...
  • Salam MA, Al-Amin MY, Salam MT, Pawar JS, Akhter N, Rabaan AA, et al. Antimicrobial Resistance: A Growing Serious Threat for Global Public...
  • Iskandar K, Molinier L, Hallit S, Sartelli M, Hardcastle TC, Haque M, et al. Surveillance of antimicrobial resistance in low- and middle-income...
  • Struelens MJ. The epidemiology of antimicrobial resistance in hospital acquired infections: problems and possible solutions. BMJ [Internet]....
  • Ahmed SK, Husein S, Qurbani K, Ibrahim RH, Fareeq A, Mahmood KA, et al. Antimicrobial resistance: Impacts, challenges, and future prospects....