Botulinum toxin in the treatment of residual limb hyperhidrosis: A systematic review

• J. Rocha Melo ^[1] ; M.A. Rodrigues ^[2] ; M. Caetano ^[2] ; P. Cantista ^[3]
  1. [1] Centro Hospitalar de Trás-os-Montes e Alto Douro, Vila Real, Portugal
  2. [2] Centro Hospitalar e Universitário do Porto, Porto, Portuga
  3. [3] Instituto de Ciências Biomédicas Abel Salazar, Porto, Portugal

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• Localización: Rehabilitación: Revista de la Sociedad Española de Rehabilitación y Medicina Física, ISSN 0048-7120, Vol. 57, Nº. 3, 2023, págs. 50-60
• Idioma: inglés
• DOI: 10.1016/j.rh.2022.07.003
• Títulos paralelos:
  • Toxina botulínica para el tratamiento de la hiperhidrosis del miembro residual: revisión sistemática
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• Resumen
  • español

    El objetivo de este estudio fue analizar la evidencia actual relacionada con el efecto de las inyecciones intradérmicas de toxina botulínica en la hiperhidrosis del miembro residual. Se realizó una búsqueda amplia en las bases de datos MEDLINE y Scopus desde su inicio hasta diciembre de 2021 con arreglo a las guías PRISMA. Los términos de la búsqueda utilizados fueron «botulinum toxins», «botulinum toxins, type A», «rimabotulinumtoxin B», «amputees», «amputation stumps», «amputation» y «residual limbs». También se utilizó el vocabulario controlado específico de cada base de datos (ej.: MeSH). Cumplieron estos criterios de búsqueda 131 estudios diferentes, que fueron revisados. Dos revisores independientes evaluaron la calidad de los documentos y 8 estudios cumplieron los criterios de inclusión. Los resultados demostraron la mejora de la hiperhidrosis del miembro residual en todos los estudios. La toxina botulínica A o B puede considerarse segura y efectiva para el tratamiento de la hiperhidrosis del miembro residual y mejora el uso de la prótesis y la calidad de vida

  • English

    The aim of the study was to analyze the current evidence regarding the effect of intradermal injections of botulinum toxin on residual limb hyperhidrosis. A comprehensive search of the MEDLINE and Scopus databases from inception until December 2021 was performed according to the PRISMA guidelines. The search terms used were ‘‘botulinum toxins’’, ‘‘botulinum toxins, Type A’’, ‘‘rimabotulinumtoxinB’’, ‘‘amputees’’, ‘‘amputation stumps’’, ‘‘amputation’’ and ‘‘residual limbs’’. The specific controlled vocabulary of each database was also used (e.g., MeSH). One hundred and thirty-one different studies met this search criteria and were reviewed. Two independent reviewers assessed the quality of the manuscripts. Eight studies met the inclusion criteria for this review. The results demonstrated an improvement in residual limb hyperhidrosis in all studies. Botulinum toxin A or B can be regarded as safe and effective for the treatment of residual limb hyperhidrosis, as well as improving prosthesis use and quality of life.

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